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According to a recent study (2018), GHK-Cu (the first generation of copper peptides) "has multiple biological actions, all of which appear to be health positive

Gene expression data: Pickart, Vasquez-Soltero, and Margolina (2015) used Broad Institute Connectivity Map data to show that GHK modulates over 4,000 human genes

doi: 10.1038/s41467-023-41631-w 181 Loc3CAR: locoregional delivery of B7-H3-specific chimeric antigen receptor autologous T cells for pediatric patients with primary CNS tumors(2023)

Copper induces oxidative stress and H 2 O 2 production in HepG2 ATP7B-KO cells After 6 h of CuCl treatment, chosen oxidative stress-related genes were significantly upregulated in HepG2 ATP7B-KO cells, while only HMOX1 showed early induction in HepG2 cells