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We found that GPX3 inhibits oxidative stress-related pathways (NFB pathway) and apoptosis-related pathways (Caspase pathway) (Figure 3B), which is consistent with our previous results
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Comparison between studies identified 52 proteins as significant in two or more studies, which were then enriched for 22 pathways, including those previously implicated in PE such as hemostasis, immune response, and lipid metabolism
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It's messed up
However, there is also a possibility that some of the effect may be independent of GLP-1, because DPP-4 inhibition still reduced -cell apoptosis in human islets cultured in the presence of exendin 9-39 (99), suggesting that other mediators might be involved, but it was also suggested that an anti-inflammatory action could have played a role (99)
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