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doi: 10.1093/molehr/gaaa081 15 GuptaSAgarwalABanerjeeJAlvarezJG

The first step is the removal of two hydrogen atoms from the 2()- and 3()-carbon atoms, catalyzed by acyl-CoA dehydrogenase and requiring FAD

Hypertension is the most common preventable risk factor for CVDs (including coronary heart disease, heart failure, stroke, myocardial infarction, atrial fibrillation, and peripheral artery disease), chronic kidney disease, and cognitive impairment, and also the main single factor for deaths and disability worldwide (133)

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Melanotan II is a synthetic analog of alpha-melanocyte-stimulating hormone (-MSH) studied for its interaction with melanocortin receptors and pigmentation-related pathways

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