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Because the data were de-identified, investigators could not confirm medication adherence or review individual charts

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December 18 Product: Xcoverys Ensacove Indication: ALK-positive locally advanced or metastatic non-small cell lung cancer Florida-based Xcovery Holdings on Thursday scored its first FDA approval with the regulatory greenlight for Ensacove (ensartinib) for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) who are also positive for the anaplastic lymphoma kinase (ALK) fusion gene

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Interestingly, treatment of patient derived erythroblasts and non-hemopoietic cells with HDACi sodium butyrate (NaBu) increased transcriptional upregulation of the G6PD gene, while having no effect on other genes in the glycolytic or PPP pathway