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Tirzepatide, marketed as Mounjaro and Zepbound, adds GIP receptor activation to GLP-1 effects

Not surprisingly, despite the evidence still being a work in progress, tapering is the strategy that is most commonly done in the office setting, says Kushner

How tirzepatide works Tirzepatide is a dual GLP-1/GIP receptor agonist used to treat type 2 diabetes and chronic weight management

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It already has a street name, a grey market with customer service, and a fan base that includes people who were never obese

For active adults, though, the same mechanisms can create a different challenge