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Multiple other causes should be considered including peripheral vascular disease, neuropathy, medication effects from other drugs (particularly diuretics, beta-agonists, and statins), hypothyroidism, pregnancy, and musculoskeletal conditions

Sold under the brand name Egrifta, tesamorelin was approved by the FDA in 2010 specifically for reducing excess abdominal fat in HIV-positive patients with lipodystrophy

At 15mg, it reached -32.9 with remarkably low heterogeneity between studies

Adv Pharmacol 27 : 431448

It has a strong affinity for copper ions, which are essential cofactors in enzyme processes related to tissue maintenance and repair

58 Median time to the development of a full symptom complex of frequency, urgency, and pain was reported to be two years in one study