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SP is then engineered with macrophage membranes (SP@M) to enable immune evasion and RA-targeting in vivo

NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes

These systems can be designed to be paintable for easy application on the epicardial surface or as microneedle patches for sequential, multi-drug delivery aligned with the pathological phases of MIRI (Lee et al., 2024

Ceramides: Locks in moisture to protect from dryness and irritation

Since 2017, Ro has helped millions of patients, including one in every county in the United States, and in 98% of primary care deserts.

These are generally transient and resolve with dose titration or as the body adapts