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Proc Natl Acad Sci USA 81:50075011 Migoya E, Miller J, Luo W-L et al (2010) Sitagliptin and metformin increase active GLP-1 by complementary mechanisms in treatment-nave patients with type 2 diabetes

This emerging theme could be further leveraged to build new in vitro antibody display libraries with long, structured CDRH3s to better engage the ECLs of class A GPCRs 65

Moreover, insulin resistance is a common pathogenic component of the development of metabolic syndrome, which is strongly associated with obesity

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Worms were qualified as dead when no locomotion could be detected and when stimulation with a wormpick did not cause a response