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a RWD: real-world data from cohort or registry studies (electronic health records, insurance-claims databases), b SRS: adverse drug reaction evidence from case reports and spontaneous-reporting systems, such as the Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) and World Health Organization (WHO) VigiBase

The findings provide crucial data, according to the researchers, to inform ongoing discussions about balancing the sustainability of health care spending against improving accessibility and affordability of GLP-1 RA medications moving forward. The trend directly informs current debates surrounding insurance coverage policies for weight-loss treatments, highlighting the challenge of reconciling costs with clinical demand and benefit