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If symptoms remain unchanged or worsen, a change in dosage might be needed

Semaglutide products are also not recommended for people with certain rare thyroid conditions

Pain control with nonsteroidal anti-inflammatory drugs, and acetaminophen should be a priority and does not result in delayed or unnecessary intervention

It's also common to lose some muscle mass along with fat while on these drugs, which can be problematic, Kessler writes

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