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NAD Precursors: Options like NMN (Nicotinamide mononucleotide) or NR (Nicotinamide riboside) may boost NAD production indirectly

The results showed a significant decrease in NRF2 mRNA expression and protein levels after treatment of breast cancer cells with Vit C and Q: the nuclear/cytosolic NRF2 ratio was reduced 1.7-fold in MDA-MB 231 cells, 2-fold in MDA-MB 468 cells, 1.4-fold in MCF-7 cells, and 1.2-fold in A549 cells

Public Health 10 , 797794 (2022)

doi: 10.1038/srep40815 (2017)