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Some fermentation effects begin within days, but meaningful shifts in microbiome composition and SCFA output typically take a few weeks of consistent fiber intake, and GLP-1 responses can continue to strengthen over months

You may also have B12 deficiency if you follow a strict vegan diet and aren't eating enough foods with B12

In these situations, your healthcare provider may recommend temporarily pausing semaglutide until the infection is fully resolved and you can maintain adequate hydration

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A qualified provider should review baseline B12 and micronutrient status before initiating MIC B12 injections