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Some studies have reported minor joint and muscle discomfort in a small percentage of patients, but the data is inconclusive

Common premixed insulins include: Humulin 70/30 (Eli Lilly) 70% NPH, 30% regular human insulin Novolin 70/30 (Novo Nordisk) same combination Humalog Mix 75/25 (Eli Lilly) 75% lispro protamine, 25% lispro Humalog Mix 50/50 (Eli Lilly) equal mix of lispro protamine and lispro NovoLog Mix 70/30 (Novo Nordisk) 70% aspart protamine, 30% aspart Before injecting any premixed insulin, always roll the pen or vial gently between your palms to mix the suspension evenly

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This includes ingredients derived from animals like pork, carnivorous animals, and blood, as well as alcohol, which is considered impure