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In these mechanisms of PGs, LTs, LXs, PAF, receptors play significant roles, therefore inhibitors or agonists of these receptors can exert therapeutic functions, and the therapeutic effects are proven in animal experiments ( Figure 3 )

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Emphasis is placed on the advances in our knowledge of the genes and proteins involved and the potential metabolic flexibility of the pathway, as well as its place within the highly intricate plant network of H 2 O 2 -metabolising systems

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This key issue is absolutely required, but quite challenging, since these two dimensions correspond to traditionaly different epistemic fields