The long-term effects of GLP-1 are not yet fully clear, but documented side effects observed within a year of usage include (in descending order of frequency) digestive system issues, abdominal and pelvic pain, nausea and vomiting, hypertension and dehydration
A reduction in proliferation, NF-B activation, migration, invasion, migration, colony formation, Cyclin D1, p-Akt, ERK-MAPK pathway, cAMP, and GSK3 accompanied this increase (Table 1)
How do they compare to true GLP-1 medications
Its not just nutrition
Those drugs mimic this hormone in a more sustained way than your body can on its own, since natural GLP-1 only sticks around in your bloodstream for a couple of minutes
Patients ask about microdosing for multiple reasons, all of which are legitimate concerns: Managing side effects