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however, they do not promote natural ovulation ( Personalized dietary therapy and weight loss, if required, are first-line treatments for young women with PCOS and obesity ( 10 (CoQ 10 ), N-acetylcysteine, and inositol, have been shown to play a therapeutic role in ameliorating inflammation and IS, restoring ovarian function, maintaining regular hormonal balance, and normalizing the menstrual cycle, and have fewer side effects with clinical significance ( Figure 1 )