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Limited human data suggests that the drug does not represent any significant risk to the baby

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Thus, the water/IPM microemulsion obtained using a 1:1 mixture (by weight) of the surfactant and cosurfactant had optimal stability, and this ratio was used for further evaluations

Consistently, the more pronounced transcriptional upregulation of profibrotic genes ( Col1a1, Fn1, Eln, Ccn2, Acta2, Col3a1 ) and kidney injury markers ( Ngal, Kim-1 ) was observed in Usp2 OE kidneys post-injury (Fig