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Its core physiological function is to catalyze the methylation of nicotinamide (NAM, a key precursor for NAD+ synthesis) with Sadenosylmethionine (SAM) to produce 1methylnicotinamide (1MNA)

If the muscles are not functioning optimally, the CCL is forced to handle excessive loads, making it prone to damage

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The total flushing volume should not be too large to prevent microbial damage

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Animal data look good