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RNAscope Tissue collection Glp1r OBhM3Dq mice ( n = 3, previously injected with viruses expressing hM3Dq-mCherry under the Glp-1r promoter control) were anaesthetised with sodium pentobarbital (50 mg/kg saline) and transcardially perfused with PBS 1X followed by 4 C PFA 4% for 5 min

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Returning food noise can reflect adaptation, but it does not justify escalating before gastrointestinal effects have resolved

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Exenatide long-acting preparations were launched in the United States in 2012 and officially launched in 2018 with the approval of the National Medical Products Administration (NMPA)

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