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In the phase 2 clinical trial, 3-26% of patients who used retatrutide experienced vomiting, compared to 1% in the placebo group

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Individuals with pronounced cardiometabolic risk factors who would benefit from its specific lipid-clearing and prediabetes reversal properties

Implications for clinical practice The increasing prescription rates of AOM semaglutide among adolescent may reflect a shift towards pharmacological interventions in managing pediatric obesity