Drug combination synergy in worm-like polymeric micelles improves treatment outcome for small cell and non-small cell lung cancer
This observation, while encouraging, must be interpreted with caution: the absence of evidence of side effects is not evidence of absence
For instance, compounds such as curcumin, resveratrol, and epigallocatechin gallate have been investigated in Phase I and Phase II studies for indications including cancer, metabolic disorders, and inflammatory diseases
The HGF/c-Met pathway that Dihexa activates is also a known pro-cancer pathway, raising unresolved safety concerns
Liver function enzymes in serum, hepatic oxidative stress, proinflammatory cytokines, apoptosis, and ER-stress biomarkers were assessed
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