We do not claim to heal, regrow hair, or stimulate collagen production
And then they get sober
Integrating genome-wide association study and expression quantitative trait loci data identifies NEGR1 as a causal risk gene of major depression disorder
FIGURE 5 5.3.1 ROS-mediated inhibition of the AMPK pathway and antioxidant defense AMP-activated protein kinase (AMPK) is a central regulator of cellular energy sensing and redox homeostasis in skeletal muscle ( 2 O 2 -mediated stimulation of LKB1 or Ca 2+ -dependent CaMKK signaling, as well as through redox-sensitive modifications such as S-glutathionylation ( Activated AMPK promotes antioxidant defense by phosphorylating Nrf2, facilitating its nuclear translocation and transcriptional induction of antioxidant enzymes including superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx)
References Pei J, Pan X, Wei G, Hua Y (2023) Research progress of glutathione peroxidase family (GPX) in redoxidation
Anti-ageing conditions including insulin resistance, diabetes, cancer, and arthritis may be defended against by glutathione