Although ALCAR exerts antioxidant activities in rodents, it is not known whether taking high doses of ALCAR will have similar effects in humans
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Dietary intake level of marine-derived DHA but not blood DHA concentration was also inversely associated with the risks of dementia and Alzheimer's disease
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Given that gut microbiota imbalances may contribute to AD progression by promoting amyloid-beta accumulation, triggering inflammation, increasing oxidative damage, and impairing insulin signaling 45,82 , these findings highlight the possibility that modulation of gut-brain axis may be a key mechanism underlying the cognitive benefits of dual-action therapies in DM2-AD comorbidity
The mean (s.d.) duration of exposure to semaglutide or placebo in the SELECT trial was 34.2 (13.7) months
