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While ALT is present only in cytoplasm, AST is present in both cytoplasm and mitochondria

For example, one might expect a dysfunctional ER to secrete proteins more slowly

"Hydroxocobalamin as a cyanide antidote: safety, efficacy and pharmacokinetics in heavily smoking normal volunteers"

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Furthermore, flow cytometry detected the changes of M1 (CD86 marker) and M2 (CD206 marker) macrophage phenotypes after various treatments