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You'll often see this ingredient paired with other ceramides (like ceramide NP), cholesterol, or fatty acids because this combination best mimics the natural lipid mix your skin already has
Copper has a complex role in oxidative biology participating in both prooxidant chemistry (where free or weakly bound copper can catalyze damaging reactive-oxygen-species generation) and antioxidant chemistry (as the cofactor of Cu/Zn superoxide dismutase)
Biochemical and preclinical investigations suggest that AOD 9604 affects pathways involved in cellular energy regulation, including cyclic AMP signaling and downstream kinase activation
If you have ever reacted to copper jewellery, copper cookware, or supplements containing copper, the topical ingredient is likely to cause the same response
Garito T, Roubenoff R, Hompesch M, Morrow L, Gomez K, Rooks D, et al
