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Indirect comparisons carry more uncertainty than a direct trial

10.1038/s42255-023-00812-z 98 OforiJ

Frequent side effects include gastrointestinal symptoms, such as nausea, vomiting, diarrhea or obstipation

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If the cause is irreversible then parental therapy should be continued for life

Another study indicates that SLC7A2-deficient mice had spontaneous inflammation in their lungs, and marked eosinophilia, associated with up-regulation of eotaxin-1, was present in the bronchoalveolar lavage fluid of 3-week-old SLC7A2-deficient mice