Interplay between alpha/beta and gamma interferons with B, T, and natural killer cells in the defense against herpes simplex virus type 1
showed that DEX increased the expression levels of SLC7A11 and GPX4 and protected H9C2 cells from hypoxia/reoxygenation injury through the AMPK/GSK-3/Nrf2 axis [233]
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Biomedicines 10:945 Saxena M, Burke A, Pavlick A, Blazquez A, Gimenez G, Meseck M, Donovan M, Rodriguez D, Castillo-Martin M et al (2022) Abstract CT108: immunogenicity of poly-ICLC matured dendritic cells as an adjuvant for NY-ESO-1 and Melan-A-MART-1 peptide vaccination compared to Montanide ISA-51 VG, in study subjects with melanoma in complete clinical remission but at high risk of disease recurrence
In another study, COVID-19 patients exhibited a reduced total antioxidant capacity but higher levels of antioxidant enzymes (superoxide dismutase and catalase) and markers of oxidative cell damage (carbonyl and lipid peroxidation) compared to controls, indicating an imbalanced redox status in these individuals [148]