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Subsequently, bacteria and endotoxins are translocated into the liver through the portal vein, activating the TLR4/NF-B signaling pathway of liver Kupffer cells, and promoting the liver inflammatory cascade and fibrosis development (Jiang and Schnabl, 2020)

A: Unlike many drugs, Dihexa dosing isn't typically weight-adjusted in research protocols

Patients should be counseled never to administer extra doses to make up for missed doses, as this could increase the risk of adverse effects without providing additional therapeutic benefit

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About two-thirds of the patients are women

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