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PubMed Zhou Y, Zhu Q, Ma W, et al

Biochim Biophys Acta (BBA) Rev Cancer

The following day the prepulse-inhibition of startle response was assessed by exposing rats to a startle stimulus (105 dB for 20 ms) preceded (100 ms) by a pre-pulse (77, 80 and 83 dB for 10 ms) repeated 10 times for each prepulse intensity at pseudo-random interval (1520 s, average of 17.5 s)

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In fact, nearly all characteristic alterations associated with ovarian aging, including metabolic disturbances, oxidative stress, impaired steroidogenesis, and dysregulation of the immune microenvironment, reflect coordinated dysfunction across multiple organelles rather than isolated deterioration of a single organelle [20]

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