PloS One (2012) 7:e37187
The formation of ice crystals can physically shred the delicate peptide chains, destroying the compound
doi: 10.3389/fendo.2024.1503905 Received 29 September 2024 Accepted 09 December 2024 Published 09 January 2025 Volume 15 - 2024 Edited by Weibin Bai, Jinan University, China Reviewed by Zia Ur Rehman, University of Agriculture, Pakistan Kamil Gill, Pomeranian Medical University, Poland Updates Copyright 2025 Saleh, Sallam, Elsuity, Dutta, Sengupta and Nasr
an explanation may be that the generation of hydrogen peroxide by the polymorphonuclear neutrophiles might cause a decrease in the quantity of reduced glutathione, whose function is to eliminate, from the red cell, the accumulated metabolites that oxidate the sulfhydryl groups formed by the oxidative stress and therefore decreasing the protective capacity of the cell
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