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However, sequential exclusion of these trials resulted in only modest changes in pooled HRs and corresponding CIs, with no substantial shifts in the direction of effect, significance, or overall interpretation of the primary findings (Supplementary Figures S5S9)

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Ozempic and Mounjaro (made by competitor Eli Lily), and the family of related drugs known as GLP-1 and GIP/GLP-1 agonists, were developed for managing Type 2 Diabetes, but soon became known for their significant effects on appetite suppression and weight loss

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10.1016/j.fsi.2019.10.040 108 XiongY.HuangX.LiY.NieY.YuH.ShiY.et al (2025)