Neuroinflammation and Brain Injury: It reduces neuroinflammation and supports nerve regeneration, potentially aiding recovery from traumatic brain injuries and protecting against neurodegeneration in conditions like Parkinsons or Alzheimers (though evidence is preliminary)
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Structures of the 26S proteasome in complex with the Hsp70 co-chaperone Bag1 reveal a mechanism for direct substrate transfer
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In that work, co-immunoprecipitation analysis showed reduced binding between caveolin-1 and eNOS, an interaction normally responsible for limiting eNOS activity