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Intriguingly, studies suggest a potential role of GLP-1 RAs in pain relief, including acute and chronic pain 65 , chronic migraine 66 , and diabetic neuropathic pain 67

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Furthermore, GLP-1R agonists could be administered as adjunct therapy to weight reduction in individuals with prior bariatric surgery, although a recent study suggested that LIRA did not promote the resolution of other obesity-related comorbidities (including OSA) compared to placebo in this population [115, 116]

Preliminary studies suggest that it can ameliorate the decline of energy metabolism in elderly individuals, showing antiaging potential