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When these mice where administered IGF-1 they showed lowered fasting glucose, and because no functional IGF-1R is present in muscle, such effect is believed to be due to renal gluconeogenesis suppression [129, 163]

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It contributes to normal muscle function, energy metabolism, and electrolyte balance, all of which matter when youre exercising as well as changing the way you eat

MMP: matrix Metalloproteinase

The choice will depend on patient preference for oral versus injectable administration, the importance of cardiovascular outcomes data, and the weight loss goals of the individual patient