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A broader mechanistic review by Seiwerth and colleagues in Current Pharmaceutical Design laid out how BPC-157 seems to borrow the same angiogenic and growth-factor pathways the body uses to heal the gut, and apply them to tendon, ligament, muscle, and bone (Seiwerth et al., 2018)

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MC4R agonism has been shown to induce synaptic changes by increasing AMPA receptors, alterations in dendritic spine densities and increasing sensitivity to glutamate

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