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Critical Appraisal Critical appraisal of the RCTs is shown in Table 2

The ESR data revealed that GHK was notably positive in reducing the concentrations of OH and ROO radicals, although it had a seemingly modest action on superoxide (O2 -) radicals

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This combination of gene regulation, ECM modulation, and anti-inflammatory signaling underscores the peptide's pleiotropic nature in laboratory investigations