Figures Abstract Insulin-degrading enzyme (IDE) is a thiol sensitive peptidase that degrades insulin and amyloid , and has been linked to type 2 diabetes mellitus and Alzheimer's disease
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Every cell in your body contains glutathione, making it one of the most important molecules for overall health maintenance
In the ferroptotic process, iron plays a pivotal role in several processes, including Fenton reaction-driven ROS production and the activation of key enzymes involved in lipid peroxidation, such as ALOX, NOX, and mitochondrial complexes I and III [103]
The overexpression of ACSL4 promotes the catalysis of various PUFAs, alters the cellular lipid composition, and ultimately increases the susceptibility of cells to ferroptosis (Cui et al., 2021)
10.1038/s41598-018-23408-0 2 Alarcn-VeleiroC.Mato-BasaloR.Lucio-GallegoS.Vidal-PampnA.Quinds-VarelaM.Al-QatarnehT.et al (2023)