Antidiabetic drugs, including intranasally administered insulin, as well as GLP-1RAs, modify the processes linking T2DM with cognitive impairment [29]
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Finally, longterm accessibility and cost of incretinbased therapies represent practical barriers for chronic neurodegenerative indications
NICE has not yet issued guidance on either agent, as appraisal processes are typically initiated only after regulatory approval, although scoping can occur earlier
Lofton suggests that nutrition guidance be tailored to a patients likes, dislikes, and lifestyle
Topiramate carries black-box warnings for acute angle-closure glaucoma, metabolic acidosis, and cognitive side effects