tirzepatide osa Sleep Apnea and Obesity: Risks, Policy, and (Zepbound®) In the two SURMOUNT-OSA trials,

This is expected and does not necessarily indicate a problem, but monitoring during the transition is important

10.1016/j.cbi.2016.10.006 155 SongX.LiZ.LiuF.WangZ.WangL

Unlike commercial weight loss programs, medical weight loss is designed to manage not only weight but also underlying conditions like diabetes, hypertension, and high cholesterol, with a goal of improving long-term health outcomes

In addition to not being a non-randomized controlled trial, criticisms of the study include that the published data was not sufficient to establish a causal association between GLP-1 receptor agonist use and NAION

Severe, persistent vomiting that prevents adequate fluid intake, intense abdominal pain, or signs of gastroparesis (severe gastric retention) warrant medical evaluation

Transl Psychiatry 8, 242 (2018)