The defining hallmark symptom of both Long COVID and ME/CFS is profound, debilitating fatigue and post-exertional malaise (PEM)
Theres a local story behind this clinic, too
Reduced cardiac and vascular inflammation has been well documented for GLP-1R agonists in experimental and human studies (Drucker, 2016)
To overcome issues such as poor adherence to dosing, muscle mass loss and other known side effects associated with GLP-1s, Rees and the team at MitoRx are pursuing a completely different method of action one that moves away from targeting food intake, instead aiming to modify the metabolism
It is a synthetic pentapeptide derived from GHRP-1 that significantly increases plasma GH levels in both animals and humans
Cagrilintide at a Glance Definition and Classification From a pharmacological perspective, cagrilintide is classified as A synthetic peptide analog A long-acting amylin analog An investigational drug currently being evaluated in Phase 3 clinical development (see the ClinicalTrials.gov study record: NCT04982575)
