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However, once pre-cancerous lesions are established, high circulating folate concentrations, particularly from excessive folic acid supplementation, may accelerate the growth of rapidly dividing cells

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ThandavarayanRAGiridharanVVArumugamSSuzukiKKoKMKrishnamurthyPet al

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We connected the whole body model of acetaminophen metabolism to our previously constructed model of glutathione metabolism[9] so that we could study the depletion of GSH after APAP doses of various sizes (Figure6)

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