retatrutide type 2 diabetes trial 2024 Effects of on body composition in people with diabetes: a substudy of a phase 2, double-blind, parallel-group, placebo-controlled, randomised Retatrutide Availability & Timeline |

Weight loss in week 1 is usually minimal (1-3 pounds, often water)

The drug lowered levels of 2-aminoadipic acid (2-AAA), triglycerides (TGs) enriched in short- and saturated-chain fatty acids, and urate in both trial populations, while 2-hydroxybutyrate (2-HB) was lowered more robustly in the T2D cohort and mainly by week 48 in the obesity trial

Compounded semaglutide is used for chronic weight management in adults with obesity or overweight

Keep vials upright and protected from light

HSA and FSA reimbursement eligibility varies by plan

Wegovy (semaglutide) is prescription-only and may not be suitable for all patients