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N Engl J Med (2015) 373:24846

It influences the production of melanin, the pigment that gives skin its color

Dieting can leave you feeling drained and weak, which makes it harder to train intensely

Gene expression Selected genes were examined: (i) genes related to mitochondrial uncoupling ( UCP1, UCP2 ), (ii) the gene encoding transmembrane protein fibronectin type III domain-containing protein 5 precursor of irisin ( FNDC5 ), and (iii) the gene involved in NAD + synthesis ( NAMPT ) (Figure 4)