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Pericytes contribute to CNS homeostasis by regulating microcirculatory flow, controlling leukocyte entry, clearing neurotoxic metabolites, modulating circadian endothelial gene expression, and maintaining astrocytic end-foot polarization (76)

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Tirzepatide works by mimicking the action of a naturally occurring hormone called glucagon-like peptide-1 (GLP-1) and blocking the action of another hormone called glucagon

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