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Figure 1 The key to understanding PEM lies in elucidating why exercise, which is generally protective in healthy individuals, induces pathological exacerbation in patients with PEM ( Thus, our study aims to synthesize pathophysiological evidence of energy metabolism, immune inflammation, and neurovascular system abnormalities observed following physical or cognitive exertion

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nipponica makino granules, derived from its extract, have shown promise in reducing thyroid autoantibody levels and rebalancing the immune system in patients with thyroid diseases

Additionally, by reducing the accumulation of lactic acid, it helps to reduce muscle soreness and improve recovery time following exercise Metabolism of Branched-Chain Amino Acids L-Carnitine also plays a role in the metabolism of branched-chain amino acids (BCAAs), which are important for muscle growth and repair

In young and metabolically healthy individuals, endogenous production may be adequate