Excessive iron ions can activate the p38-MAPK pathway and block the PI3K/AKT and JAK/STAT3 signaling pathways, thereby inducing death in MC3T3-E1 cells [149]
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doi: 10.2174/157340607780620662 31 Rotondo DottoreGChiariniRDe GregorioMLeoMCasiniGCestariLet al