This group primarily encompasses a range of rare and complex conditions, including multiple sclerosis, autoimmune encephalitis, neuromyelitis optica spectrum disorders, autoimmune epilepsy, myasthenia gravis, and central nervous system demyelinating diseases, among others, and affects individuals across a wide age range [170]
EZH2, the H3K27 methyltransferase responsible for gene silencing, shows 2.4-fold increased activity, reinforcing repressive chromatin states in spermatogonial cells (94)
2000 Jun;165(3):569-77
The antioxidant properties help to protect the skin from UV-induced damage, reducing the risk of sunburn, photo ageing, and DNA damage
By examining the latest advancements in our understanding of these interactions, we aim to illuminate potential therapeutic strategies and identify areas for future research
In addition, to further test the reliability of the results and to reduce the error due to sample overlap, we performed validation using the latest data from the FinnGen (www.finngen.fi) database, version R11