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In addition, the analysis of the EXSCEL trial revealed that a composite end-point of new macroalbuminuria, 40% eGFR decline or renal death was reduced by the addition of exenatide in T2DM [26]

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Two phase II trials - one in a population with obesity (without T2D) [45], and a second in a population with T2D and overweight/obesity [46], have recently been published and their key findings are presented below (Table 1)