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It occurs naturally in human plasma and declines sharply with age from around 200 ng/mL at age 20 to roughly 80 ng/mL by age 60

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However, knee extension strength was markedly lower on the surgical versus nonsurgical side

Research is being done to discover how certain hormonessuch as pregnenolone, DHEA, and testosteronemay influence the nervous system and pain receptors

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