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10.1146/annurev-publhealth-031912-114409 303

When left unchecked, free radicals can cause oxidative damage to our cells, DNA, proteins, and lipids

Thats a big problem with no clear solution.

Of 500 genes on chromosome 21, 18 genes influence gene expression, and more than 20 genes are involved in metabolic functioning (Sturgeon and Gardiner 2011)

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A click without medication delivery usually indicates an air lock (trapped air preventing plunger movement) or a needle that hasn't fully pierced the cartridge septum